en.wikipedia.org/wiki/Ramatroban
2 corrections found
Ramatroban is indicated for the treatment of coronary artery disease.
This indication is wrong. Official Baynas/ramatroban labeling identifies it as a medicine for allergic rhinitis, not coronary artery disease.
Full reasoning
The claim says ramatroban is indicated for coronary artery disease, but the product labeling for Baynas tablets 50 mg / 75 mg (ramatroban) identifies the drug as a "Medicine for allergic rhinitis". The same labeling lists the Japanese approval and marketing information for Baynas/ramatroban and does not present coronary artery disease as the approved indication. A current company description of ramatroban likewise says it has been used in Japan for the treatment of allergic rhinitis. Together, these sources directly contradict the article's statement about coronary artery disease.
2 sources
- Baynas tablets 50 mg / 75 mg Medical Interview Form (Ramatroban)
"ProstaglandinD2 and Thromboxane A2 receptor antagonists" ... "Medicine for allergic rhinitis" ... "Baynas tablets 50 mg" / "Baynas tablets 75 mg".
- Our Science | KARE Biosciences
"Ramatroban (Baynas®, Bayer, Japan; dose: 50 mg and 75 mg tablets oral BID) ... has been safely and effectively used for the treatment of allergic rhinitis in Japan for the past 20 years."
although no clinical trial has yet been conducted.
This is outdated. A registered Phase 2/3 randomized placebo-controlled clinical trial of ramatroban for hospitalized COVID-19 patients exists.
Full reasoning
This sentence is no longer correct. A registered ClinicalTrials.gov study, NCT05706454, is a Phase 2/Phase 3 trial evaluating ramatroban plus standard of care versus placebo plus standard of care in subjects hospitalized for COVID-19 pneumonia / SARS-CoV-2 infection. KARE Biosciences also states that ramatroban "is currently being tested in a randomized placebo-controlled trial of hospitalized COVID-19 patients in India (RAMBAN-1)." Because a clinical trial has in fact been registered and conducted/tested, the statement that "no clinical trial has yet been conducted" is incorrect.
2 sources
- ClinicalTrials.gov: NCT05706454 - Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Subjects Hospitalized For COVID Pneumonia
"Phase II/Phase III study to evaluate the safety and efficacy of Ramatroban 75 mg tablet against Placebo in subjects hospitalized for pneumonia due to SARS-CoV-2 infection."
- Our Science | KARE Biosciences
"Ramatroban (KAR101) is currently being tested in a randomized placebo-controlled trial of hospitalized COVID-19 patients in India (RAMBAN-1)."