www.midwesterndoctor.com/p/healing-back-pain-and-ending-the
2 corrections found
at typical doses they cause a 5 to 15% loss of bone every year
The cited review does not say glucocorticoids cause 5–15% bone loss every year. It says bone loss can be 5–15% during the first year of treatment, with slower loss thereafter.
Full reasoning
This sentence overstates the bone-loss rate from glucocorticoids.
The review the article cites says: "bone loss ... can be 5–15% during the first year of treatment". It does not say patients lose 5–15% of bone every year indefinitely. The same review immediately adds that the increased rate of bone loss persists more slowly in chronic users.
A separate meta-analysis of 1-year glucocorticoid effects quantified the average loss as much smaller than the article claims: mean 1-year bone loss was -1.7% in the lumbar spine and -1.3% in the femoral neck overall, and -3.6% / -3.1% in high-dose cohorts. So the article converts a "first year" estimate into an "every year" estimate and materially exaggerates ongoing annual bone loss.
2 sources
- Glucocorticoid-induced osteoporosis - PMC
According to a meta-analysis of 56 cross-sectional studies and 10 longitudinal studies, bone loss assessed by dual-energy X-ray absorptiometry, can be 5–15% during the first year of treatment... The increased rate of bone loss persists in chronic GC users, but more slowly.
- One-year effects of glucocorticoids on bone density: a meta-analysis in cohorts on high and low-dose therapy
The mean 1-year bone loss in the lumbar spine was -1.7% and in the femoral neck -1.3%; in high-dose cohorts it was -3.6% in the lumbar spine and -3.1% in the femoral neck.
with no correlation between imaging findings and pain severity
The evidence does not support a blanket claim of 'no correlation' between MRI findings and pain severity. Recent cohort and systematic-review data found small but real associations, especially when multiple degenerative findings are present.
Full reasoning
This statement is too absolute.
It is true that many MRI abnormalities are seen in people without back pain, and MRI findings alone should not be treated as a one-to-one explanation for symptoms. But saying there is "no correlation" between imaging findings and pain severity is not what the literature shows.
A 2022 population-based cohort study reported that pain severity was slightly higher in people with MRI findings, and that having multiple MRI findings (five or more) was associated with mildly greater pain severity at baseline and with a greater increase in pain severity over 6 years among participants who were pain-free at baseline.
A 2025 systematic review likewise found that most studies reported stronger associations between increasing summed MRI findings and low back pain, and several studies found the same pattern for low-back-pain-related disability. In other words, the associations are often weak or not clinically decisive, but they are not literally zero.
So the article turns a nuanced conclusion (MRI findings are often weak, nonspecific, and not sufficient to explain pain by themselves) into an incorrect absolute claim (no correlation at all).
2 sources
- Association of Lumbar MRI Findings with Current and Future Back Pain in a Population-based Cohort Study
Pain severity was slightly higher in those with MRI findings... Compared to zero MRI findings, having multiple MRI findings (five or more) was associated with mildly greater pain-severity at baseline (0.84; 0.50-1.17) and greater increase in pain-severity over 6 years in those pain free at baseline (1.21; 0.04-2.37).
- Associations Between Sum Scores or Combinations of MRI Findings in the Lumbar Spine and Low Back Pain-Related Outcomes: A Systematic Review - PMC
Most studies reported stronger associations between increasing sum scores of MRI findings and LBP... Eight of 11 studies reported stronger associations between increasing findings and LBP, and five of eight found the same for LBP-related disability.